FDCSP

Across TCGA patient cohorts, FDCSP mutation is significantly associated with the RNA expression of many other genes, with 242 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FDCSP-associated genes across cancer lineages are RNA5SP401, CYCSP26, and MTND1P33. Each is linked with FDCSP in more than 1 cancer types. Because this analysis shows association rather than direction, both FDCSP-to-partner and partner-to-FDCSP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP401 grouped by FDCSP-low versus FDCSP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FDCSP→partner) and Y-score (partner→FDCSP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP401 →	+0.181	+4.469	.004	.006	3	2
LUSC	CYCSP26 →	+0.102	+4.393	<.001	.008	3	2
SKCM	MTND1P33 →	+0.033	+4.624	<.001	.005	3	1
SKCM	SOCS5P3 →	+0.080	+3.403	<.001	.006	3	1
SKCM	LINC02862 →	+0.131	+3.630	.001	.004	3	1
SKCM	TUBAP8 →	+0.065	+4.015	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 242 associations by consensus.

RNA5SP401 by FDCSP expression — SKCM

Explore this box plot interactively →