FCRL4

Across TCGA cell cohorts, FCRL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 167 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FCRL4-associated GO terms across cancer lineages are Negative regulation of autophagosome maturation, Positive regulation of type I interferon production, and Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion. Each is linked with FCRL4 in more than 3 cancer types. Because this analysis shows association rather than direction, both FCRL4-to-partner and partner-to-FCRL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagosome maturation grouped by FCRL4-low versus FCRL4-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCRL4→partner) and Y-score (partner→FCRL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of autophagosome maturation →	+0.089	+0.808	<.001	.006	3	4
CNS	Positive regulation of type I interferon production →	+0.046	+0.002	.001	.001	3	3
CNS	Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion →	-0.076	-0.002	.008	.001	3	3
BLOOD_Lymphoma	Regulation of immune complex clearance by monocytes and macrophages →	+1.395	+0.562	<.001	.005	3	3
BLOOD_Myeloma	Protein import into peroxisome matrix, translocation →	-0.116	-0.545	<.001	.008	3	2
BLOOD_Myeloma	P38MAPK cascade →	+0.081	+0.334	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 167 associations by consensus.

Negative regulation of autophagosome maturation by FCRL4 expression — BLOOD_Lymphoma

Explore this box plot interactively →