FCMR

Across TCGA patient cohorts, FCMR RNA expression is significantly associated with the protein abundance of many other proteins, with 19,701 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FCMR-associated proteins across cancer lineages are ARHGAP45, PTPN7, and ARHGAP25. Each is linked with FCMR in more than 9 cancer types. Because this analysis shows association rather than direction, both FCMR-to-partner and partner-to-FCMR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCMR versus ARHGAP45 in LSCC, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FCMR→partner) and Y-score (partner→FCMR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGAP45 →	+0.582	+1.259	<.001	<.001	3	10
LSCC	PTPN7 →	+0.503	+1.156	<.001	<.001	3	10
OV	ARHGAP25 →	+0.810	+0.898	.002	<.001	3	10
LSCC	RCSD1 →	+0.605	+1.162	<.001	<.001	3	10
OV	SASH3 →	+0.697	+1.010	<.001	<.001	3	10
GBM	SEPTIN1 →	+1.088	+0.607	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,701 associations by consensus.

FCMR vs ARHGAP45 — LSCC

Explore this scatter interactively →