FCMR

Across TCGA cell cohorts, FCMR RNA expression is significantly associated with the go_rna of many other GO terms, with 5,305 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCMR-associated GO terms across cancer lineages are Positive regulation of natural killer cell differentiation, Regulation of dendritic cell apoptotic process, and Regulation of plasminogen activation. Each is linked with FCMR in more than 10 cancer types. Because this analysis shows association rather than direction, both FCMR-to-partner and partner-to-FCMR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of natural killer cell differentiation grouped by FCMR-low versus FCMR-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCMR→partner) and Y-score (partner→FCMR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of natural killer cell differentiation →	+0.695	+0.922	.005	.003	3	11
BONE	Regulation of dendritic cell apoptotic process →	+0.775	+0.924	.003	<.001	3	10
LIVER	Regulation of plasminogen activation →	+0.309	+1.403	<.001	<.001	3	10
LIVER	Positive regulation of triglyceride catabolic process →	+0.146	+1.167	.008	.006	2	11
BONE	Regulation of protein maturation →	+0.180	+0.862	.001	.003	3	10
LIVER	Negative regulation of dendritic cell apoptotic process →	+1.790	+1.125	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,305 associations by consensus.

Positive regulation of natural killer cell differentiation by FCMR expression — LIVER

Explore this box plot interactively →