FCHO2

Across TCGA patient cohorts, FCHO2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,900 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FCHO2-associated genes across cancer lineages are SLCO2B1, ADGRE4P, and MS4A6A. Each is linked with FCHO2 in more than 6 cancer types. Because this analysis shows association rather than direction, both FCHO2-to-partner and partner-to-FCHO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCHO2 versus SLCO2B1 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHO2→partner) and Y-score (partner→FCHO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLCO2B1 →	+0.911	+0.290	<.001	<.001	3	7
GBM	ADGRE4P →	+0.904	+0.208	<.001	.001	3	7
GBM	MS4A6A →	+0.999	+0.272	<.001	<.001	3	6
HNSC	CD244 →	+0.816	+0.286	<.001	<.001	3	6
UCEC	RIPK3 →	+0.733	+0.203	.004	.001	3	6
LSCC	CHIT1 →	+1.053	+0.276	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,900 associations by consensus.

FCHO2 vs SLCO2B1 — HNSC

Explore this scatter interactively →