FCHO2

Across TCGA patient cohorts, FCHO2 mutation is significantly associated with the RNA expression of many other genes, with 4,170 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCHO2-associated genes across cancer lineages are RN7SL134P, FAM223B, and RN7SKP182. Each is linked with FCHO2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FCHO2-to-partner and partner-to-FCHO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by FCHO2-low versus FCHO2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCHO2→partner) and Y-score (partner→FCHO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL134P →	+0.099	+3.289	<.001	.003	3	3
BRCA	FAM223B →	+0.082	+5.505	<.001	.002	3	2
LUAD	RN7SKP182 →	+0.424	+4.631	<.001	.008	3	2
LUAD	RNA5SP365 →	+0.329	+4.554	<.001	.009	3	2
UCEC	PTCD1 →	+0.224	+3.024	.003	<.001	3	2
UCEC	C1QBP →	+0.697	+2.378	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,170 associations by consensus.

RN7SL134P by FCHO2 expression — CESC

Explore this box plot interactively →