FCGR3B

Across TCGA patient cohorts, FCGR3B protein abundance is significantly associated with the RNA expression of many other genes, with 4,507 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FCGR3B-associated genes across cancer lineages are CXCR1, CXCR2, and VNN3. Each is linked with FCGR3B in more than 3 cancer types. Because this analysis shows association rather than direction, both FCGR3B-to-partner and partner-to-FCGR3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCGR3B versus CXCR1 in PDAC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR3B→partner) and Y-score (partner→FCGR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CXCR1 →	+1.859	+1.919	<.001	<.001	3	4
PDAC	CXCR2 →	+1.349	+1.462	<.001	.001	3	4
PDAC	VNN3 →	+0.859	+1.781	<.001	<.001	3	4
HNSC	SEMA6B →	+0.721	+1.424	.001	<.001	3	3
LUAD	CSF3 →	+1.432	+1.242	<.001	<.001	3	3
PDAC	MEFV →	+0.903	+2.053	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,507 associations by consensus.

FCGR3B vs CXCR1 — PDAC

Explore this scatter interactively →