FCGR3B

Across TCGA cell cohorts, FCGR3B RNA expression is significantly associated with the go_rna of many other GO terms, with 680 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FCGR3B-associated GO terms across cancer lineages are Regulation of protein export from nucleus, Regulation of nucleocytoplasmic transport, and Positive regulation of tumor necrosis factor-mediated signaling pathway. Each is linked with FCGR3B in more than 5 cancer types. Because this analysis shows association rather than direction, both FCGR3B-to-partner and partner-to-FCGR3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein export from nucleus grouped by FCGR3B-low versus FCGR3B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR3B→partner) and Y-score (partner→FCGR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of protein export from nucleus →	+0.083	+0.018	.001	.005	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of nucleocytoplasmic transport →	+0.054	+0.017	.001	.008	3	5
CNS	Positive regulation of tumor necrosis factor-mediated signaling pathway →	+0.095	+0.011	<.001	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Antigen processing and presentation of endogenous antigen →	+0.263	+0.028	<.001	.002	3	4
UPPER_AERODIGESTIVE_TRACT	Intracellular receptor signaling pathway →	+0.041	+0.022	.001	<.001	3	4
BLOOD_Lymphoma	Positive regulation of response to cytokine stimulus →	+0.073	+0.134	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 680 associations by consensus.

Regulation of protein export from nucleus by FCGR3B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →