Across TCGA patient cohorts, FCGR3A mutation is significantly associated with the RNA expression of many other genes, with 801 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCGR3A-associated genes across cancer lineages are RNA5SP411, PDSS1P2, and LINC01734. Each is linked with FCGR3A in more than 1 cancer types. Because this analysis shows association rather than direction, both FCGR3A-to-partner and partner-to-FCGR3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR3A→partner) and Y-score (partner→FCGR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+1.057	+2.808	.001	<.001	3	2
LUAD	PDSS1P2 →	+0.159	+3.892	<.001	.008	3	2
LUAD	LINC01734 →	+0.038	+4.303	.001	.009	3	2
LUAD	MTHFD2P3 →	+0.225	+4.928	<.001	<.001	3	2
LUAD	MIR3199-1 →	+0.729	+4.445	<.001	.002	3	2
LUAD	GAGE2E →	+0.297	+4.612	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 801 associations by consensus.

Exploration

FCGR3A survival (RNA) · tumor vs normal (RNA) · all FCGR3A data types