FCGR2C

Across TCGA patient cohorts, FCGR2C mutation is significantly associated with the RNA expression of many other genes, with 431 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCGR2C-associated genes across cancer lineages are SNORD115-5, MIR4425, and RNA5SP459. Each is linked with FCGR2C in more than 1 cancer types. Because this analysis shows association rather than direction, both FCGR2C-to-partner and partner-to-FCGR2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD115-5 grouped by FCGR2C-low versus FCGR2C-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2C→partner) and Y-score (partner→FCGR2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNORD115-5 →	+0.393	+7.954	<.001	.008	3	2
STAD	MIR4425 →	+0.416	+5.105	<.001	.008	3	2
COAD	RNA5SP459 →	+0.433	+6.568	<.001	<.001	3	2
LGG	RNU4ATAC10P →	+0.238	+7.977	<.001	.007	3	2
UCEC	ATP6V1E1P2 →	+0.192	+2.340	<.001	.003	3	2
COAD	LINC02543 →	+0.130	+4.807	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 431 associations by consensus.

SNORD115-5 by FCGR2C expression — HNSC

Explore this box plot interactively →