FCGR2C

Across TCGA cell cohorts, FCGR2C RNA expression is significantly associated with the go_rna of many other GO terms, with 2,198 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCGR2C-associated GO terms across cancer lineages are Antibody-dependent cellular cytotoxicity, Type IIa hypersensitivity, and Type II hypersensitivity. Each is linked with FCGR2C in more than 6 cancer types. Because this analysis shows association rather than direction, both FCGR2C-to-partner and partner-to-FCGR2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antibody-dependent cellular cytotoxicity grouped by FCGR2C-low versus FCGR2C-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2C→partner) and Y-score (partner→FCGR2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Antibody-dependent cellular cytotoxicity →	+1.447	+1.280	<.001	<.001	3	7
SKIN	Type IIa hypersensitivity →	+1.447	+1.280	<.001	<.001	3	7
SKIN	Type II hypersensitivity →	+1.447	+1.280	<.001	<.001	3	7
BREAST	Protein polyubiquitination →	+0.034	+0.121	<.001	.007	3	5
BLOOD_Lymphoma	Negative regulation of dendritic cell differentiation →	+1.253	+1.501	<.001	<.001	3	4
BLOOD_Leukemia	Negative regulation of antigen processing and presentation →	+0.354	+1.660	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,198 associations by consensus.

Antibody-dependent cellular cytotoxicity by FCGR2C expression — SKIN

Explore this box plot interactively →