FCGR2B

Across TCGA patient cohorts, FCGR2B mutation is significantly associated with the RNA expression of many other genes, with 1,708 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCGR2B-associated genes across cancer lineages are MIR4480, TRAJ57, and RNU2-51P. Each is linked with FCGR2B in more than 1 cancer types. Because this analysis shows association rather than direction, both FCGR2B-to-partner and partner-to-FCGR2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4480 grouped by FCGR2B-low versus FCGR2B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2B→partner) and Y-score (partner→FCGR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4480 →	+0.278	+4.469	<.001	.006	3	2
UCEC	TRAJ57 →	+0.436	+2.470	.001	.005	3	2
UCEC	RNU2-51P →	+0.568	+2.222	<.001	.004	3	2
UCEC	RNU6-416P →	+0.184	+2.977	.001	.009	3	2
COAD	LSM1P1 →	+0.533	+4.893	<.001	.005	3	2
LUAD	RNU6-75P →	+0.365	+5.327	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,708 associations by consensus.

MIR4480 by FCGR2B expression — SKCM

Explore this box plot interactively →