FCGR1A

Across TCGA pan-cancer cohorts, FCGR1A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FCGR1A data layer compared with 19 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher FCGR1A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FCGR1A expression acts as an unfavorable survival marker.

LIHC, SKCM, and LUSC are the cancer types where FCGR1A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	II,III,IV	0.051	0.716	<.001	24	view →
SKCM	DFS	Median	All	0.396	0.765	.005	10	view →
LUSC	OS	Median	All	0.180	0.659	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FCGR1A–LIHC (OS)

Open the LIHC breakdown →