FCGR1A

Across TCGA patient cohorts, FCGR1A protein abundance is significantly associated with the RNA expression of many other genes, with 17,706 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FCGR1A-associated genes across cancer lineages are FCGR2A, C1QC, and FCGR1B. Each is linked with FCGR1A in more than 8 cancer types. Because this analysis shows association rather than direction, both FCGR1A-to-partner and partner-to-FCGR1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCGR1A versus FCGR2A in GBM, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR1A→partner) and Y-score (partner→FCGR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FCGR2A →	+1.174	+0.853	<.001	<.001	3	9
GBM	C1QC →	+1.320	+0.886	<.001	<.001	3	9
GBM	FCGR1B →	+0.927	+0.863	<.001	<.001	3	9
OV	FCGR3A →	+1.463	+0.573	<.001	<.001	3	9
GBM	MSR1 →	+1.102	+0.780	<.001	<.001	3	9
GBM	CYTH4 →	+1.106	+0.851	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,706 associations by consensus.

FCGR1A vs FCGR2A — GBM

Explore this scatter interactively →