FCF1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FCF1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,897 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FCF1-associated genes across cancer lineages are WDR43, EIF3E, and LRPPRC. Each is linked with FCF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FCF1-to-partner and partner-to-FCF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCF1 versus WDR43 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCF1→partner) and Y-score (partner→FCF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCWDR43 →+0.597+0.322<.001<.00134
LSCCEIF3E →+0.487+0.392<.001.00334
LSCCLRPPRC →+0.505+0.375<.001<.00134
LSCCSNHG1 →+0.765+0.480<.001<.00134
BRCAPSAT1 →+1.755+0.396<.001<.00134
BRCAPDSS1 →+0.650+0.403.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,897 associations by consensus.

FCF1 vs WDR43 — LSCC

Per-sample scatter of FCF1 vs WDR43 in LSCC (Pearson r = 0.50).

Explore this scatter interactively →

Exploration