FCF1

Across TCGA patient cohorts, FCF1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCF1-associated genes across cancer lineages are Skeletal muscle, mv Endothelial cells, and Plasma cells. Each is linked with FCF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FCF1-to-partner and partner-to-FCF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skeletal muscle grouped by FCF1-low versus FCF1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCF1→partner) and Y-score (partner→FCF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Skeletal muscle →	+0.052	+2.813	.024	.037	3	1
UCEC	mv Endothelial cells →	-0.028	-3.159	.030	.020	2	1
UCEC	Plasma cells →	-0.027	-3.127	.021	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Skeletal muscle by FCF1 expression — SKCM

Explore this box plot interactively →