FCF1

Across TCGA cell cohorts, FCF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,928 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FCF1-associated GO terms across cancer lineages are Mitotic G2/M transition checkpoint, Immunoglobulin heavy chain V-D-J recombination, and Negative regulation of G2/M transition of mitotic cell cycle. Each is linked with FCF1 in more than 13 cancer types. Because this analysis shows association rather than direction, both FCF1-to-partner and partner-to-FCF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic G2/M transition checkpoint grouped by FCF1-low versus FCF1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCF1→partner) and Y-score (partner→FCF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Mitotic G2/M transition checkpoint →	+0.086	+0.855	<.001	.002	3	14
OESOPHAGUS	Immunoglobulin heavy chain V-D-J recombination →	+0.169	+0.707	.004	.003	3	13
LUNG_NSCLC_LUSC	Negative regulation of G2/M transition of mitotic cell cycle →	+0.074	+1.008	.006	.004	3	13
BLOOD_Lymphoma	Negative regulation of cell cycle G2/M phase transition →	+0.070	+1.309	<.001	<.001	3	13
BREAST	Protein localization to condensed chromosome →	+0.118	+1.136	<.001	<.001	3	13
SKIN	Monoubiquitinated protein deubiquitination →	+0.125	+0.930	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,928 associations by consensus.

Mitotic G2/M transition checkpoint by FCF1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →