FCER2

Across TCGA patient cohorts, FCER2 mutation is significantly associated with the RNA expression of many other genes, with 1,536 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCER2-associated genes across cancer lineages are RN7SL248P, GPR180, and CENPH. Each is linked with FCER2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FCER2-to-partner and partner-to-FCER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by FCER2-low versus FCER2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCER2→partner) and Y-score (partner→FCER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL248P →	+0.212	+7.584	<.001	<.001	3	3
UCEC	GPR180 →	+0.485	+2.724	.004	.003	3	2
UCEC	CENPH →	+0.612	+3.592	.002	.001	3	2
UCEC	SKA1 →	+0.714	+3.480	.001	.002	3	2
UCEC	DONSON →	+0.496	+3.202	.003	.009	3	2
UCEC	RBM15 →	+0.398	+3.098	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,536 associations by consensus.

RN7SL248P by FCER2 expression — CESC

Explore this box plot interactively →