Across TCGA patient cohorts, FCAR protein abundance is significantly associated with the RNA expression of many other genes, with 7,945 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FCAR-associated genes across cancer lineages are MEFV, CSF3R, and TREM1. Each is linked with FCAR in more than 6 cancer types. Because this analysis shows association rather than direction, both FCAR-to-partner and partner-to-FCAR results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCAR→partner) and Y-score (partner→FCAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MEFV →	+1.356	+2.003	<.001	<.001	3	7
COAD	CSF3R →	+1.820	+1.302	<.001	<.001	3	7
COAD	TREM1 →	+1.791	+1.513	<.001	<.001	3	7
OV	CXCL1 →	+3.320	+1.172	.002	.008	3	7
COAD	BCL2A1 →	+2.235	+1.451	<.001	<.001	3	7
COAD	FCGR3B →	+2.890	+1.320	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,945 associations by consensus.

Exploration

FCAR survival (RNA) · tumor vs normal (RNA) · all FCAR data types