Across TCGA patient cohorts, FCAR mutation is significantly associated with the RNA expression of many other genes, with 753 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FCAR-associated genes across cancer lineages are RNA5SP413, RPS20P33, and RNA5SP415. Each is linked with FCAR in more than 3 cancer types. Because this analysis shows association rather than direction, both FCAR-to-partner and partner-to-FCAR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCAR→partner) and Y-score (partner→FCAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+1.341	+2.277	<.001	.001	3	4
UCEC	RPS20P33 →	+0.534	+2.343	.003	.003	3	3
LUSC	RNA5SP415 →	+0.841	+4.733	<.001	<.001	3	3
UCEC	MVD →	+0.573	+2.748	.002	.003	3	2
UCEC	THOP1 →	+0.483	+2.332	.005	.003	3	2
UCEC	TOP3A →	+0.483	+2.732	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 753 associations by consensus.

Exploration

FCAR survival (RNA) · tumor vs normal (RNA) · all FCAR data types