Across TCGA cell cohorts, FCAR mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FCAR-associated genes across cancer lineages are ADAMDEC1, TOPAZ1, and ARGFX. Each is linked with FCAR in more than 1 cancer types. Because this analysis shows association rather than direction, both FCAR-to-partner and partner-to-FCAR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCAR→partner) and Y-score (partner→FCAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ADAMDEC1 →	+0.032	+5.189	<.001	<.001	3	1
LUNG_NSCLC_LUAD	TOPAZ1 →	+0.009	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	ARGFX →	+0.024	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	LCE2C →	+0.031	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR11A1 →	+0.046	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR10C1 →	+0.050	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

FCAR survival (RNA) · tumor vs normal (RNA) · all FCAR data types