FCAMR

Across TCGA cell cohorts, FCAMR mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FCAMR-associated genes across cancer lineages are TEX36, OR52N5, and MOG. Each is linked with FCAMR in more than 1 cancer types. Because this analysis shows association rather than direction, both FCAMR-to-partner and partner-to-FCAMR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX36 grouped by FCAMR-low versus FCAMR-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCAMR→partner) and Y-score (partner→FCAMR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TEX36 →	+0.084	+2.878	<.001	.009	3	1
LARGE_INTESTINE	OR52N5 →	+0.038	+3.700	<.001	.009	3	1
LARGE_INTESTINE	MOG →	+0.107	+3.376	<.001	.002	3	1
LARGE_INTESTINE	ACOT6 →	+0.097	+2.878	.004	.009	3	1
LARGE_INTESTINE	GSG1L2 →	+0.011	+3.700	<.001	.009	3	1
LARGE_INTESTINE	CCL18 →	+0.057	+4.000	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

TEX36 by FCAMR expression — LARGE_INTESTINE

Explore this box plot interactively →