FBXW5

Across TCGA patient cohorts, FBXW5 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,002 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FBXW5-associated proteins across cancer lineages are SEC16A, RAB14, and TRAF2. Each is linked with FBXW5 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXW5-to-partner and partner-to-FBXW5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXW5 versus SEC16A in UCEC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXW5→partner) and Y-score (partner→FBXW5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEC16A →	+0.237	+1.005	<.001	.007	3	6
OV	RAB14 →	+0.312	+0.765	<.001	<.001	3	5
OV	TRAF2 →	+0.282	+0.508	<.001	<.001	3	5
COAD	EHMT1 →	+0.366	+0.473	<.001	<.001	3	4
PDAC	FPGS →	+0.355	+0.377	.002	.001	2	5
UCEC	PAXX →	+0.373	+1.487	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,002 associations by consensus.

FBXW5 vs SEC16A — UCEC

Explore this scatter interactively →