FBXW4P1

Across TCGA pan-cancer cohorts, FBXW4P1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated FBXW4P1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FBXW4P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FBXW4P1 expression acts as an unfavorable survival marker, although some lineages such as STAD and LAML show a favorable association.

KIRC, UVM, and ACC are the cancer types where FBXW4P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.710	0.869	<.001	80	view →
UVM	DFS	Quartile	All	0.498	0.952	<.001	66	view →
ACC	OS	Median	III,IV	0.235	0.713	.002	50	view →
COAD	DFS	Quartile	II,III,IV	0.428	0.787	.005	29	view →
STAD	OS	Quartile	All	0.743	0.407	.001	28	view →
THCA	DFS	Quartile	III,IV	0.499	0.928	.004	26	view →
LAML	DFS	Median	All	0.482	0.264	.005	22	view →
LGG	OS	Median	All	0.531	0.381	<.001	21	view →
READ	DFS	Quartile	All	0.708	0.263	.027	15	view →
UCS	OS	Tertile	IV	0.241	0.675	.036	12	view →
PRAD	DFS	Tertile	All	0.732	0.894	.017	12	view →
OV	DFS	Median	IV	0.349	0.567	.007	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

FBXW4P1–KIRC (DFS)

Open the KIRC breakdown →