FBXW4

Across TCGA patient cohorts, FBXW4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,382 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FBXW4-associated proteins across cancer lineages are NHLRC2, PEBP1, and NAA15. Each is linked with FBXW4 in more than 6 cancer types. Because this analysis shows association rather than direction, both FBXW4-to-partner and partner-to-FBXW4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXW4 versus NHLRC2 in UCEC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXW4→partner) and Y-score (partner→FBXW4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NHLRC2 →	+0.265	+0.605	.002	.001	3	7
BRCA	PEBP1 →	+0.291	+0.446	.006	.002	3	6
GBM	NAA15 →	-0.212	-0.504	<.001	<.001	3	5
BRCA	EEF1G →	-0.270	-0.471	<.001	<.001	3	5
BRCA	EEF2_T435 →	-0.735	-0.647	.005	.001	3	5
GBM	HDLBP →	-0.234	-0.389	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,382 associations by consensus.

FBXW4 vs NHLRC2 — UCEC

Explore this scatter interactively →