FBXW4

Across TCGA cell cohorts, FBXW4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,385 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXW4-associated GO terms across cancer lineages are Flagellated sperm motility, Sperm motility, and Cilium or flagellum-dependent cell motility. Each is linked with FBXW4 in more than 14 cancer types. Because this analysis shows association rather than direction, both FBXW4-to-partner and partner-to-FBXW4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Flagellated sperm motility grouped by FBXW4-low versus FBXW4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXW4→partner) and Y-score (partner→FBXW4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Flagellated sperm motility →	-0.136	-1.376	<.001	<.001	3	15
OESOPHAGUS	Sperm motility →	-0.136	-1.376	<.001	<.001	3	15
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.123	-1.417	<.001	<.001	3	14
OESOPHAGUS	Cilium-dependent cell motility →	-0.123	-1.417	<.001	<.001	3	14
OESOPHAGUS	Cilium movement involved in cell motility →	-0.128	-1.508	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium movement →	-0.075	-0.719	.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,385 associations by consensus.

Flagellated sperm motility by FBXW4 expression — OESOPHAGUS

Explore this box plot interactively →