FBXW10

Across TCGA patient cohorts, FBXW10 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,704 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXW10-associated proteins across cancer lineages are NAXE, NOL9, and TAF2_S1185. Each is linked with FBXW10 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBXW10-to-partner and partner-to-FBXW10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXW10 versus NAXE in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXW10→partner) and Y-score (partner→FBXW10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NAXE →	+0.342	+0.528	<.001	<.001	3	3
LSCC	NOL9 →	+0.329	+0.537	<.001	<.001	3	3
BRCA	TAF2_S1185 →	+0.812	+0.397	.001	.004	3	3
LSCC	TALDO1 →	+0.414	+0.398	<.001	<.001	3	3
GBM	MVP →	-0.702	-0.436	<.001	<.001	3	3
LSCC	PPP1R18 →	-0.327	-0.522	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,704 associations by consensus.

FBXW10 vs NAXE — LSCC

Explore this scatter interactively →