FBXO9

Across TCGA patient cohorts, FBXO9 mutation is significantly associated with the RNA expression of many other genes, with 1,113 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO9-associated genes across cancer lineages are MIR6877, MIR6766, and USP37P1. Each is linked with FBXO9 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO9-to-partner and partner-to-FBXO9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6877 grouped by FBXO9-low versus FBXO9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO9→partner) and Y-score (partner→FBXO9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6877 →	+0.468	+3.875	<.001	.006	3	2
UCEC	MIR6766 →	+0.255	+2.432	<.001	.003	3	2
STAD	USP37P1 →	+0.150	+5.026	<.001	.009	3	2
BLCA	RPL22P13 →	+0.163	+4.208	.005	.009	3	2
HNSC	RNU6-956P →	+0.763	+7.954	<.001	.008	3	2
SKCM	CTBP2P9 →	+0.041	+4.495	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,113 associations by consensus.

MIR6877 by FBXO9 expression — SKCM

Explore this box plot interactively →