FBXO9

Across TCGA cell cohorts, FBXO9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,441 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXO9-associated GO terms across cancer lineages are Cytosolic transport, Positive regulation of TORC2 signaling, and Vacuole organization. Each is linked with FBXO9 in more than 12 cancer types. Because this analysis shows association rather than direction, both FBXO9-to-partner and partner-to-FBXO9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by FBXO9-low versus FBXO9-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO9→partner) and Y-score (partner→FBXO9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.088	+1.106	<.001	.004	3	13
SKIN	Positive regulation of TORC2 signaling →	+0.092	+0.542	<.001	<.001	3	13
BLOOD_Myeloma	Vacuole organization →	+0.057	+0.937	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Mitotic cytokinesis →	+0.101	+1.035	<.001	.001	3	13
PANCREAS	Negative regulation of DNA-templated transcription initiation →	+0.119	+0.856	.001	<.001	3	12
SKIN	Regulation of protein sumoylation →	+0.109	+0.505	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,441 associations by consensus.

Cytosolic transport by FBXO9 expression — UPPER_AERODIGESTIVE_TRACT

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