FBXO9

Across TCGA cell cohorts, FBXO9 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO9-associated genes across cancer lineages are PPP1R2C and TMCO5A. Each is linked with FBXO9 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO9-to-partner and partner-to-FBXO9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPP1R2C grouped by FBXO9-low versus FBXO9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO9→partner) and Y-score (partner→FBXO9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PPP1R2C →	+0.046	+4.095	<.001	.009	3	1
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PPP1R2C by FBXO9 expression — LARGE_INTESTINE

Explore this box plot interactively →