FBXO8

Across TCGA patient cohorts, FBXO8 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,658 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FBXO8-associated proteins across cancer lineages are ARFIP1, TOP1, and UTP20. Each is linked with FBXO8 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXO8-to-partner and partner-to-FBXO8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO8 versus ARFIP1 in LUAD, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO8→partner) and Y-score (partner→FBXO8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ARFIP1 →	+0.291	+0.542	<.001	<.001	3	6
COAD	TOP1 →	-0.421	-0.536	<.001	<.001	3	5
UCEC	UTP20 →	-0.359	-0.862	<.001	<.001	3	5
PDAC	WDR43 →	-0.285	-0.315	<.001	<.001	3	5
COAD	SETD7 →	+0.378	+0.466	.003	<.001	3	5
LUAD	CKAP4_S26 →	-1.041	-0.401	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,658 associations by consensus.

FBXO8 vs ARFIP1 — LUAD

Explore this scatter interactively →