FBXO7

Across TCGA cell cohorts, FBXO7 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO7-associated genes across cancer lineages are SMIM14, CFAP47, and CX3CR1. Each is linked with FBXO7 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO7-to-partner and partner-to-FBXO7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM14 grouped by FBXO7-low versus FBXO7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO7→partner) and Y-score (partner→FBXO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SMIM14 →	+1.004	+3.064	.005	.009	3	1
LARGE_INTESTINE	CFAP47 →	+0.264	+2.938	<.001	.003	3	1
LARGE_INTESTINE	CX3CR1 →	+0.133	+3.215	.002	.009	3	1
LARGE_INTESTINE	OR13J1 →	+0.043	+3.215	.002	.009	3	1
LARGE_INTESTINE	CYB5D1 →	+1.171	+3.082	<.001	.007	3	1
LARGE_INTESTINE	FAM153B →	+0.374	+2.648	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

SMIM14 by FBXO7 expression — LARGE_INTESTINE

Explore this box plot interactively →