FBXO6

Across TCGA patient cohorts, FBXO6 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,768 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FBXO6-associated proteins across cancer lineages are STAT1, OAS2, and OAS3. Each is linked with FBXO6 in more than 8 cancer types. Because this analysis shows association rather than direction, both FBXO6-to-partner and partner-to-FBXO6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO6 versus STAT1 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO6→partner) and Y-score (partner→FBXO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	STAT1 →	+0.714	+1.132	<.001	<.001	3	9
GBM	OAS2 →	+0.795	+0.323	<.001	.002	3	8
HNSC	OAS3 →	+0.651	+0.684	<.001	.004	3	8
HNSC	PARP14 →	+0.505	+0.852	<.001	.002	3	8
LSCC	FBXO6_S284 →	+0.780	+0.439	<.001	<.001	3	8
BRCA	TAP1 →	+0.676	+0.633	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,768 associations by consensus.

FBXO6 vs STAT1 — HNSC

Explore this scatter interactively →