FBXO6

Across TCGA patient cohorts, FBXO6 protein abundance is significantly associated with the RNA expression of many other genes, with 14,699 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FBXO6-associated genes across cancer lineages are IFIH1, STAT1, and GBP1. Each is linked with FBXO6 in more than 7 cancer types. Because this analysis shows association rather than direction, both FBXO6-to-partner and partner-to-FBXO6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO6 versus IFIH1 in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO6→partner) and Y-score (partner→FBXO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IFIH1 →	+1.033	+0.450	<.001	.001	3	8
OV	STAT1 →	+0.860	+0.552	<.001	<.001	3	8
UCEC	GBP1 →	+1.166	+0.463	.002	<.001	3	8
GBM	XAF1 →	+1.234	+0.378	<.001	<.001	3	8
HNSC	IFI44L →	+1.393	+0.616	<.001	<.001	3	8
COAD	UBE2L6 →	+1.028	+0.593	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,699 associations by consensus.

FBXO6 vs IFIH1 — OV

Explore this scatter interactively →