FBXO48

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FBXO48 mutation is significantly associated with the RNA expression of many other genes, with 1,393 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO48-associated genes across cancer lineages are RNA5SP412, RNU6-650P, and MIR548U. Each is linked with FBXO48 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO48-to-partner and partner-to-FBXO48 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO48→partner) and Y-score (partner→FBXO48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP412 →+0.654+2.230<.001.00532
COADRNU6-650P →+0.364+4.392<.001.00632
COADMIR548U →+0.999+4.547<.001.00532
UCECMIR4510 →+0.165+3.338<.001.00432
UCECDNAH8-AS1 →+0.072+2.352.009.00132
UCECRNA5SP182 →+0.265+3.761.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,393 associations by consensus.

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