FBXO48

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FBXO48 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO48-associated genes across cancer lineages are ZNF831 and CDX4. Each is linked with FBXO48 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO48-to-partner and partner-to-FBXO48 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO48→partner) and Y-score (partner→FBXO48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEZNF831 →+0.013+3.688<.001.00231
LARGE_INTESTINECDX4 →+0.013+3.632<.001.00331
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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