Across TCGA patient cohorts, FBXO47 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO47-associated genes across cancer lineages are p62 Lck ligand, ATM, and Bcl-2. Each is linked with FBXO47 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO47-to-partner and partner-to-FBXO47 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO47→partner) and Y-score (partner→FBXO47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.670	+3.807	<.001	<.001	3	2
UCEC	ATM →	-0.709	-3.156	<.001	.018	3	2
UCEC	Bcl-2 →	-0.397	-2.999	.011	.035	3	2
UCEC	PCNA →	+0.283	+2.700	.003	.006	3	1
UCEC	PDK1_pS241 →	+0.155	+3.000	.044	.036	3	1
UCEC	PDK1 →	+0.115	+3.013	.017	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

FBXO47 survival (RNA) · tumor vs normal (RNA) · all FBXO47 data types