FBXO46

Across TCGA patient cohorts, FBXO46 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,792 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FBXO46-associated proteins across cancer lineages are PPP5C, IRF2BP1, and LIG1. Each is linked with FBXO46 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXO46-to-partner and partner-to-FBXO46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO46 versus PPP5C in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO46→partner) and Y-score (partner→FBXO46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP5C →	+0.343	+0.918	<.001	<.001	3	6
BRCA	IRF2BP1 →	+0.382	+0.595	<.001	<.001	3	6
LSCC	LIG1 →	+0.549	+0.583	<.001	<.001	3	6
GBM	TRIM28 →	+0.391	+0.320	<.001	<.001	3	6
GBM	SMC3 →	+0.303	+0.270	<.001	<.001	3	6
GBM	DHX9 →	+0.282	+0.396	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,792 associations by consensus.

FBXO46 vs PPP5C — OV

Explore this scatter interactively →