FBXO42

Across TCGA patient cohorts, FBXO42 protein abundance is significantly associated with the RNA expression of many other genes, with 12,875 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO42-associated genes across cancer lineages are UBE4B, SNRPE, and ZFP36L1. Each is linked with FBXO42 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBXO42-to-partner and partner-to-FBXO42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO42 versus UBE4B in OV, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO42→partner) and Y-score (partner→FBXO42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	UBE4B →	+0.599	+0.439	.007	.006	3	3
OV	SNRPE →	-0.588	-0.700	<.001	<.001	3	3
OV	ZFP36L1 →	+0.890	+0.438	.001	.003	3	3
PDAC	SNORA63C →	+1.324	+0.320	<.001	.002	3	3
LSCC	RPL22L1 →	-0.788	-0.214	<.001	<.001	3	3
BRCA	NBPF1 →	+0.584	+0.200	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,875 associations by consensus.

FBXO42 vs UBE4B — OV

Explore this scatter interactively →