FBXO41

Across TCGA patient cohorts, FBXO41 protein abundance is significantly associated with the RNA expression of many other genes, with 3,286 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FBXO41-associated genes across cancer lineages are PRODH, GRK3, and SEZ6L. Each is linked with FBXO41 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO41-to-partner and partner-to-FBXO41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO41 versus PRODH in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO41→partner) and Y-score (partner→FBXO41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.838	+0.457	<.001	<.001	3	1
GBM	GRK3 →	+0.386	+0.438	.005	.001	3	1
GBM	SEZ6L →	+1.515	+0.413	<.001	<.001	3	1
GBM	LGALS1 →	-0.554	-0.346	.006	.008	3	1
GBM	SOX10 →	+1.553	+0.445	<.001	<.001	3	1
GBM	SLC16A8 →	+0.667	+0.531	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,286 associations by consensus.

FBXO41 vs PRODH — GBM

Explore this scatter interactively →