FBXO41

Across TCGA pan-cancer cohorts, FBXO41 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of FBXO41’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where FBXO41 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FBXO41 is over-expressed in tumor.

COAD, HNSC, and KIRC are the cancer types where FBXO41 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FBXO41 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+2.124	<.001	12	view →
HNSC	Male	IV	+1.755	<.001	11	view →
KIRC	Male	All	+0.960	<.001	11	view →
BLCA	All	All	+1.361	<.001	10	view →
THCA	Female	III,IV	+1.662	<.001	9	view →
LUAD	All	III,IV	+1.218	<.001	9	view →
KIRP	All	All	+0.885	<.001	9	view →
STAD	Male	II,III,IV	+1.412	<.001	8	view →
LUSC	Female	All	+1.509	<.001	6	view →
BRCA	All	All	+0.616	<.001	6	view →
LIHC	All	All	+0.280	<.001	4	view →
CHOL	All	All	+1.980	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

FBXO41–COAD

Open the COAD breakdown →