FBXO41

Across TCGA cell cohorts, FBXO41 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO41-associated genes across cancer lineages are OR10V1, DYNAP, and CNBD1. Each is linked with FBXO41 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO41-to-partner and partner-to-FBXO41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10V1 grouped by FBXO41-low versus FBXO41-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO41→partner) and Y-score (partner→FBXO41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR10V1 →	+0.040	+4.017	<.001	.007	3	2
STOMACH	DYNAP →	+0.128	+4.129	<.001	.007	3	2
LARGE_INTESTINE	CNBD1 →	+0.270	+3.562	<.001	.002	3	2
OESOPHAGUS	IFNK →	+0.038	+4.392	<.001	.003	3	1
OESOPHAGUS	OR8B2 →	+0.040	+4.392	<.001	.003	3	1
SKIN	PGK2 →	+0.034	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

OR10V1 by FBXO41 expression — OESOPHAGUS

Explore this box plot interactively →