FBXO4

Across TCGA patient cohorts, FBXO4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,502 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO4-associated genes across cancer lineages are C5, MYCBPAP, and NNT. Each is linked with FBXO4 in more than 4 cancer types. Because this analysis shows association rather than direction, both FBXO4-to-partner and partner-to-FBXO4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO4 versus C5 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO4→partner) and Y-score (partner→FBXO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	C5 →	+0.837	+0.446	<.001	<.001	3	5
UCEC	MYCBPAP →	+0.802	+0.283	<.001	.004	3	5
HNSC	NNT →	+0.741	+0.476	<.001	<.001	3	5
UCEC	DNAJB13 →	+0.993	+0.269	<.001	.005	3	5
GBM	DTHD1 →	+1.045	+0.224	.001	<.001	3	4
UCEC	IDNK →	+0.663	+0.334	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,502 associations by consensus.

FBXO4 vs C5 — HNSC

Explore this scatter interactively →