FBXO38

Across TCGA cell cohorts, FBXO38 mutation is significantly associated with the RNA expression of many other genes, with 135 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO38-associated genes across cancer lineages are TLX3, CST9L, and GCAT. Each is linked with FBXO38 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO38-to-partner and partner-to-FBXO38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TLX3 grouped by FBXO38-low versus FBXO38-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO38→partner) and Y-score (partner→FBXO38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TLX3 →	+2.054	+3.266	<.001	.003	3	2
SOFT_TISSUE	CST9L →	+0.032	+5.369	<.001	.004	3	1
LARGE_INTESTINE	GCAT →	+1.146	+3.364	.005	.002	3	1
LARGE_INTESTINE	CBY1 →	+0.579	+3.160	.003	.006	3	1
LARGE_INTESTINE	IL7 →	+0.789	+3.451	.005	.002	3	1
LARGE_INTESTINE	NDUFC1 →	+0.660	+3.364	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 135 associations by consensus.

TLX3 by FBXO38 expression — BLOOD_Leukemia

Explore this box plot interactively →