FBXO36

Across TCGA patient cohorts, FBXO36 mutation is significantly associated with the RNA expression of many other genes, with 851 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO36-associated genes across cancer lineages are RNASEH1, LAPTM4BP2, and AUP1. Each is linked with FBXO36 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO36-to-partner and partner-to-FBXO36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASEH1 grouped by FBXO36-low versus FBXO36-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO36→partner) and Y-score (partner→FBXO36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNASEH1 →	+0.720	+3.332	.001	.005	3	2
UCEC	LAPTM4BP2 →	+0.699	+3.354	<.001	.005	3	2
UCEC	AUP1 →	+0.357	+3.354	.004	.005	3	2
UCEC	ILKAP →	+0.484	+3.210	.002	.009	3	2
UCEC	ST13P10 →	+0.182	+3.044	.004	.001	3	2
UCEC	AHCYP4 →	+0.141	+2.815	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 851 associations by consensus.

RNASEH1 by FBXO36 expression — UCEC

Explore this box plot interactively →