FBXO36

Across TCGA cell cohorts, FBXO36 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,350 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXO36-associated GO terms across cancer lineages are Otolith mineralization, Protein localization to cilium, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with FBXO36 in more than 9 cancer types. Because this analysis shows association rather than direction, both FBXO36-to-partner and partner-to-FBXO36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Otolith mineralization grouped by FBXO36-low versus FBXO36-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO36→partner) and Y-score (partner→FBXO36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Otolith mineralization →	+0.093	+0.856	<.001	<.001	3	10
BREAST	Protein localization to cilium →	+0.069	+0.833	<.001	<.001	3	9
BLOOD_Leukemia	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.056	+0.462	<.001	<.001	3	8
BLOOD_Lymphoma	Vesicle coating →	+0.061	+0.366	<.001	<.001	3	8
LUNG_SCLC	Intraciliary anterograde transport →	+0.119	+0.858	<.001	.003	3	8
SKIN	Protein localization to ciliary transition zone →	+0.042	+0.523	.006	.005	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,350 associations by consensus.

Otolith mineralization by FBXO36 expression — LUNG_NSCLC_LUAD

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