FBXO36

Across TCGA cell cohorts, FBXO36 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO36-associated genes across cancer lineages are SSMEM1, CPLX4, and KRTAP7-1. Each is linked with FBXO36 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO36-to-partner and partner-to-FBXO36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSMEM1 grouped by FBXO36-low versus FBXO36-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO36→partner) and Y-score (partner→FBXO36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SSMEM1 →	+0.038	+3.707	<.001	.009	3	1
LARGE_INTESTINE	CPLX4 →	+0.027	+4.392	.001	.004	3	1
LARGE_INTESTINE	KRTAP7-1 →	+0.048	+4.437	<.001	.004	3	1
LARGE_INTESTINE	ADAM7 →	+0.005	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SSMEM1 by FBXO36 expression — LARGE_INTESTINE

Explore this box plot interactively →