FBXO33

Across TCGA pan-cancer cohorts, FBXO33 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of FBXO33’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where FBXO33 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types FBXO33 is over-expressed in tumor, although a few such as HNSC and CCRCC show the opposite, repressed pattern.

LUAD, HNSC, and CCRCC are the cancer types where FBXO33 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FBXO33 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	+0.296	<.001	6	view →
HNSC	All	III,IV	−0.415	.034	2	view →
CCRCC	All	All	−0.177	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

FBXO33–LUAD

Open the LUAD breakdown →