FBXO33

Across TCGA patient cohorts, FBXO33 protein abundance is significantly associated with the RNA expression of many other genes, with 847 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FBXO33-associated genes across cancer lineages are RGL2, POPDC2, and GTSF1L. Each is linked with FBXO33 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO33-to-partner and partner-to-FBXO33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO33 versus RGL2 in HNSC, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO33→partner) and Y-score (partner→FBXO33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RGL2 →	-1.295	-0.845	.001	.005	3	2
OV	POPDC2 →	-1.120	-0.790	.003	.006	3	2
LSCC	GTSF1L →	-0.219	-0.367	<.001	<.001	3	2
LSCC	GEMIN2 →	+0.644	+0.444	<.001	<.001	3	2
CCRCC	ACTG1P22 →	+0.673	+0.330	<.001	.005	3	2
HNSC	SLC8A2 →	+0.315	+1.022	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 847 associations by consensus.

FBXO33 vs RGL2 — HNSC

Explore this scatter interactively →