FBXO33

Across TCGA patient cohorts, FBXO33 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,750 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FBXO33-associated proteins across cancer lineages are CLIP1_S312, REEP3_T201, and GPATCH8_S1081. Each is linked with FBXO33 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO33-to-partner and partner-to-FBXO33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO33 versus CLIP1_S312 in GBM, with a Pearson correlation of -0.56.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO33→partner) and Y-score (partner→FBXO33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CLIP1_S312 →	-0.574	-0.392	.002	.001	3	2
GBM	REEP3_T201 →	+0.973	+0.725	<.001	<.001	3	2
BRCA	GPATCH8_S1081 →	+0.868	+0.446	.002	<.001	3	2
GBM	BAZ2A →	+0.339	+0.573	<.001	<.001	3	1
GBM	BEND3_S164 →	+0.620	+0.570	.003	<.001	3	1
GBM	C8orf34_S433 →	-0.732	-0.659	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,750 associations by consensus.

FBXO33 vs CLIP1_S312 — GBM

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